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Trazodone shares side effects common to many antidepressants.
The most frequent of these are dry mouth, constipation, and urinary retention, though these are less common than with tricyclic antidepressants.
Trazodone is the most sedating, and least anticholinergic, of all the currently marketed antidepressants.Trazodone is available as 50-mg, 100-mg, and 150-mg film-coated tablets that cannot be divided, and 150-mg and 300-mg oral tablets that can be split.Therapy is usually started at a total of 150 mg per day divided into two or three doses.Before starting treatment, people with these conditions should discuss the relative risks and benefits of treatment with their doctors to help determine if protriptyline is the right antidepressant for them.Trazodone may increase heart rate and stress on the heart.
Some artificial saliva products may give temporary relief.